• SKIP TO CONTENT
  • SKIP NAVIGATION
  • Patient Resources
    • COVID-19 Patient Resource Center
    • Clinical Trials
    • Search Clinical Trials
    • Patient Notification System
    • What is Clinical Research?
    • Volunteering for a Clinical Trial
    • Understanding Informed Consent
    • Useful Resources
    • FDA Approved Drugs
  • Professional Resources
    • Research Center Profiles
    • Clinical Trial Listings
    • Market Research
    • FDA Approved Drugs
    • Training Guides
    • Books
    • eLearning
    • Events
    • Newsletters
    • White Papers
    • SOPs
    • eCFR and Guidances
  • White Papers
  • Trial Listings
  • Advertise
  • COVID-19
  • iConnect
  • Sign In
  • Create Account
  • Sign Out
  • My Account
Home » Shire's Cinryze label expanded for pediatric use

Shire's Cinryze label expanded for pediatric use

March 20, 2017
CenterWatch Staff

Shire announced that the European Commission (EC) has approved a label extension for drug Cinryze for use in pediatrics.

Consequently, Cinryze is now approved for routine prevention of angioedema attacks in children (aged 6 years and above) with severe and recurrent attacks of hereditary angioedema (HAE) who are intolerant to or insufficiently protected by oral preventions treatments, or patients who are inadequately managed with repeated acute treatments.

The drug is now approved for the treatment and pre-procedure prevention of angioedema attacks in children (aged 2 years and above) with HAE.   

The drug was approved for these indications in adults and adolescents aged 12-17 years with HA since 2011.

Cinryze recorded sales of $680.2 million in 2016, up 10% driven by an increase in the number of patients on therapy which was partially offset by reduced utilization as a result of a supply constraint in the U.S. during the second half of the year.

A label expansion of the drug is likely to boost sales further. Shire acquired ViroPharma in 2014 and added Cinryze to its portfolio. Cinryze complements Shire's Firazyr, which is indicated for the on-demand treatment of acute HAE attacks. The acquisition of Dyax added Kalbitor to Shire’s HAE portfolio.

Upcoming Events

  • 16Feb

    Fundamentals of FDA Inspection Management: Reduce Anxiety, Increase Inspection Success

  • 21May

    WCG MAGI Clinical Research Conference – 2023 East

Featured Products

  • Spreadsheet Validation: Tools and Techniques to Make Data in Excel Compliant

    Spreadsheet Validation: Tools and Techniques to Make Data in Excel Compliant

  • Surviving an FDA GCP Inspection

    Surviving an FDA GCP Inspection: Resources for Investigators, Sponsors, CROs and IRBs

Featured Stories

  • SurveywBlueBackground-360x240.png

    Sites Name Tech Acceptance as Essential Factor in Selection of Sponsors, Survey Finds

  • TrendsInsights2023-360x240.png

    WCG Clinical Research Trends and Insights for 2023, Part Two

  • TimeMoneyEffort-360x240.png

    Time is Money and So Is Effort, Budgeting Experts Say

  • TrendsInsights2023A-360x240.png

    WCG Clinical Research Trends and Insights for 2023, Part Three

Standard Operating Procedures for Risk-Based Monitoring of Clinical Trials

The information you need to adapt your monitoring plan to changing times.

Learn More Here
  • About Us
  • Contact Us
  • Privacy Policy
  • Do Not Sell or Share My Data

Footer Logo

300 N. Washington St., Suite 200, Falls Church, VA 22046, USA

Phone 617.948.5100 – Toll free 866.219.3440

Copyright © 2023. All Rights Reserved. Design, CMS, Hosting & Web Development :: ePublishing